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Core Binding Factors are essential for ovulation, luteinization, and female fertility in mice

Core Binding Factors (CBFs) are a small group of heterodimeric transcription factor complexes composed of DNA binding proteins, RUNXs, and a non-DNA binding protein, CBFB. The LH surge increases the expression of Runx1 and Runx2 in ovulatory follicles, while Cbfb is constitutively expressed. To inve...

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Detalles Bibliográficos
Autores principales: Lee-Thacker, Somang, Jeon, Hayce, Choi, Yohan, Taniuchi, Ichiro, Takarada, Takeshi, Yoneda, Yukio, Ko, CheMyong, Jo, Misung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303197/
https://www.ncbi.nlm.nih.gov/pubmed/32555437
http://dx.doi.org/10.1038/s41598-020-64257-0