Backbone Interactions Between Transcriptional Activator ExsA and Anti-Activator ExsD Facilitate Regulation of the Type III Secretion System in Pseudomonas aeruginosa

The type III secretion system (T3SS) is a pivotal virulence mechanism of many Gram-negative bacteria. During infection, the syringe-like T3SS injects cytotoxic proteins directly into the eukaryotic host cell cytoplasm. In Pseudomonas aeruginosa, expression of the T3SS is regulated by a signaling cas...

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Detalles Bibliográficos
Autores principales: Shrestha, Manisha, Bernhards, Robert C., Fu, Yichen, Ryan, Kylie, Schubot, Florian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303211/
https://www.ncbi.nlm.nih.gov/pubmed/32555263
http://dx.doi.org/10.1038/s41598-020-66555-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303211/
https://www.ncbi.nlm.nih.gov/pubmed/32555263
http://dx.doi.org/10.1038/s41598-020-66555-z

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