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NAMPT and BMAL1 Are Independently Involved in the Palmitate-Mediated Induction of Neuroinflammation in Hypothalamic Neurons

Obesity is a prominent metabolic disease that predisposes individuals to multiple comorbidities, including type 2 diabetes mellitus, cardiovascular diseases, and cancer. Elevated circulating levels of fatty acids contribute to the development of obesity, in part, by targeting the hypothalamus. Palmi...

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Detalles Bibliográficos
Autores principales: Tran, Andy, He, Wenyuan, Jiang, Nan, Chen, Jim T. C., Belsham, Denise D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303266/
https://www.ncbi.nlm.nih.gov/pubmed/32595600
http://dx.doi.org/10.3389/fendo.2020.00351