P2X7 Receptor Antagonism as a Potential Therapy in Amyotrophic Lateral Sclerosis

This review focuses on the purinergic ionotropic receptor P2X7 (P2X7R) as a potential target for developing drugs that delay the onset and/or disease progression in patients with amyotrophic lateral sclerosis (ALS). Description of clinical and genetic ALS features is followed by an analysis of advan...

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Detalles Bibliográficos
Autores principales: Ruiz-Ruiz, Cristina, Calzaferri, Francesco, García, Antonio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303288/
https://www.ncbi.nlm.nih.gov/pubmed/32595451
http://dx.doi.org/10.3389/fnmol.2020.00093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303288/
https://www.ncbi.nlm.nih.gov/pubmed/32595451
http://dx.doi.org/10.3389/fnmol.2020.00093

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