Pathogenic Mutations Differentially Regulate Cell-to-Cell Transmission of α-Synuclein

Recent studies suggest that the cell-to-cell spread of pathological α-synuclein (α-syn) plays important roles in the development of Parkinson’s disease (PD). PD patients who carry α-syn gene mutations often have an earlier onset and more severe clinical symptoms and pathology than sporadic PD cases...

Descripción completa

Detalles Bibliográficos
Autores principales: Guan, Yuan, Zhao, Xiaofang, Liu, Fengwei, Yan, Shuxin, Wang, Yalong, Du, Cuilian, Cui, Xiuyu, Li, Rena, Zhang, Claire Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303300/
https://www.ncbi.nlm.nih.gov/pubmed/32595456
http://dx.doi.org/10.3389/fncel.2020.00159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303300/
https://www.ncbi.nlm.nih.gov/pubmed/32595456
http://dx.doi.org/10.3389/fncel.2020.00159

Ejemplares similares