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Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer’s dementia

INTRODUCTION: Metabotropic glutamate receptors play a critical role in the pathogenesis of Alzheimer's disease due to their involvement in processes of memory formation, neuroplasticity, and synaptotoxity. The objective of the current study was to study mGluR5 availability measured by [(11)C]‐A...

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Detalles Bibliográficos
Autores principales: Treyer, Valerie, Gietl, Anton F., Suliman, Husam, Gruber, Esmeralda, Meyer, Rafael, Buchmann, Andreas, Johayem, Anass, Unschuld, Paul G., Nitsch, Roger M., Buck, Alfred, Ametamey, Simon M., Hock, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303388/
https://www.ncbi.nlm.nih.gov/pubmed/32304284
http://dx.doi.org/10.1002/brb3.1632