A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

SARS-CoV-2 has caused the COVID-19 pandemic. There is an urgent need for physiological models to study SARS-CoV-2 infection using human disease-relevant cells. COVID-19 pathophysiology includes respiratory failure but involves other organ systems including gut, liver, heart, and pancreas. We present...

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Detalles Bibliográficos
Autores principales: Yang, Liuliu, Han, Yuling, Nilsson-Payant, Benjamin E., Gupta, Vikas, Wang, Pengfei, Duan, Xiaohua, Tang, Xuming, Zhu, Jiajun, Zhao, Zeping, Jaffré, Fabrice, Zhang, Tuo, Kim, Tae Wan, Harschnitz, Oliver, Redmond, David, Houghton, Sean, Liu, Chengyang, Naji, Ali, Ciceri, Gabriele, Guttikonda, Sudha, Bram, Yaron, Nguyen, Duc-Huy T., Cioffi, Michele, Chandar, Vasuretha, Hoagland, Daisy A., Huang, Yaoxing, Xiang, Jenny, Wang, Hui, Lyden, David, Borczuk, Alain, Chen, Huanhuan Joyce, Studer, Lorenz, Pan, Fong Cheng, Ho, David D., tenOever, Benjamin R., Evans, Todd, Schwartz, Robert E., Chen, Shuibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303620/
https://www.ncbi.nlm.nih.gov/pubmed/32579880
http://dx.doi.org/10.1016/j.stem.2020.06.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303620/
https://www.ncbi.nlm.nih.gov/pubmed/32579880
http://dx.doi.org/10.1016/j.stem.2020.06.015

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