Cargando…

3Scover: Identifying Safeguard TF from Cell Type-TF Specificity Network by an Extended Minimum Set Cover Model

Transcription factors (TFs) define cellular identity either by activating target cell program or by silencing donor program as demonstrated by intensive cell reprogramming studies. Here, we propose an extended minimum set cover model with stable selection (3Scover) to systematically identify silenci...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Qiuyue, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303665/
https://www.ncbi.nlm.nih.gov/pubmed/32554189
http://dx.doi.org/10.1016/j.isci.2020.101227