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Club Cell Heme Oxygenase-1 Deletion: Effects in Hyperoxia-Exposed Adult Mice

Thioredoxin reductase-1 (TXNRD1) inhibition activates nuclear factor (erythroid-derived 2)-like 2 (Nrf2) responses and prevents acute lung injury (ALI). Heme oxygenase-1 (HO-1) induction following TXNRD1 inhibition is Nrf2-dependent in airway epithelial (club) cells in vitro. The influence of club c...

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Detalles Bibliográficos
Autores principales: Dunigan-Russell, Katelyn, Silverberg, Mary, Lin, Vivian Y., Li, Rui, Wall, Stephanie B., Li, Qian, Nicola, Teodora, Gotham, John, Crowe, David R., Vitiello, Peter F., Agarwal, Anupam, Tipple, Trent E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303751/
https://www.ncbi.nlm.nih.gov/pubmed/32587658
http://dx.doi.org/10.1155/2020/2908271