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P2X7 receptor antagonist recovers ileum myenteric neurons after experimental ulcerative colitis

BACKGROUND: The P2X7 receptor is expressed by enteric neurons and enteric glial cells. Studies have demonstrated that administration of a P2X7 receptor antagonist, brilliant blue G (BBG), prevents neuronal loss. AIM: To report the effects of BBG in ileum enteric neurons immunoreactive (ir) following...

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Detalles Bibliográficos
Autores principales: Souza, Roberta Figueiroa, Evangelinellis, Mariá Munhoz, Mendes, Cristina Eusébio, Righetti, Marta, Lourenço, Múcio Cevulla Silva, Castelucci, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303980/
https://www.ncbi.nlm.nih.gov/pubmed/32587788
http://dx.doi.org/10.4291/wjgp.v11.i4.84