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Sex differences in Alzheimer’s-related Tau biomarkers and a mediating effect of testosterone

Women show greater pathological Tau biomarkers than men along the Alzheimer’s disease (AD) continuum, particularly among apolipoprotein ε-E4 (APOE4) carriers; however, the reason for this sex difference in unknown. Sex differences often indicate an underlying role of sex hormones. We examined whethe...

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Detalles Bibliográficos
Autores principales: Sundermann, Erin E., Panizzon, Matthew S., Chen, Xu, Andrews, Murray, Galasko, Douglas, Banks, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304096/
https://www.ncbi.nlm.nih.gov/pubmed/32560743
http://dx.doi.org/10.1186/s13293-020-00310-x