Antagonizing CDK8 Sensitizes Colorectal Cancer to Radiation Through Potentiating the Transcription of e2f1 Target Gene apaf1

Radiotherapy is an essential curative treatment modality for colorectal cancer. Apoptosis is the major mechanism of IR-induced cell death and aberrant apoptotic signaling results in radioresistance, which is a hallmark of most, perhaps all, types of human cancers. Potentiating the induction of apopt...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Wen, Pengbo, Hu, Guanshuo, Gao, Yang, Qi, Xiaojing, Zhu, Kaili, Chen, Shaopeng, Wu, Lijun, Xu, An, Zhao, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304162/
https://www.ncbi.nlm.nih.gov/pubmed/32596239
http://dx.doi.org/10.3389/fcell.2020.00408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304162/
https://www.ncbi.nlm.nih.gov/pubmed/32596239
http://dx.doi.org/10.3389/fcell.2020.00408

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