Phosphorylation and oligomerization of α-synuclein associated with GSK-3β activation in the rTg4510 mouse model of tauopathy

Neurodegenerative diseases are characterized by the accumulation of specific phosphorylated protein aggregates in the brain, such as hyperphosphorylated tau (hp-tau) in tauopathies and phosphorylated α-synuclein (p-αSyn) in α-synucleinopathies. The simultaneous accumulation of different proteins is...

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Detalles Bibliográficos
Autores principales: Takaichi, Yuta, Chambers, James K., Inoue, Hiroyuki, Ano, Yasuhisa, Takashima, Akihiko, Nakayama, Hiroyuki, Uchida, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304163/
https://www.ncbi.nlm.nih.gov/pubmed/32560668
http://dx.doi.org/10.1186/s40478-020-00969-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304163/
https://www.ncbi.nlm.nih.gov/pubmed/32560668
http://dx.doi.org/10.1186/s40478-020-00969-8

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