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RalB degradation by dihydroartemisinin induces autophagy and IFI16/caspase-1 inflammasome depression in the human laryngeal squamous cell carcinoma

BACKGROUND: Interferon-inducible 16 (IFI16)/caspase-1 inflammasome activates and secretes IL-1β. However, it is still unclear whether the IFI16 inflammasome is involved in human laryngeal squamous cell carcinoma. Autophagy directly removed inflammasome components and limited early IL-1β production....

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Detalles Bibliográficos
Autores principales: Shi, Xinli, Li, Shenghao, Wang, Li, Li, Hui, Li, Zhen, Wang, Weiyi, Bai, Jing, Sun, Yajing, Li, Jianchun, Li, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304197/
https://www.ncbi.nlm.nih.gov/pubmed/32577124
http://dx.doi.org/10.1186/s13020-020-00340-y