Cargando…
Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer
BACKGROUND: Metabolic reprograming, non-mutational epigenetic changes, increased cell plasticity, and multidrug tolerance are early hallmarks of therapy resistance in cancer. In this temporary, therapy-tolerant state, cancer cells are highly sensitive to ferroptosis, a form of regulated cell death t...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304214/ https://www.ncbi.nlm.nih.gov/pubmed/32577235 http://dx.doi.org/10.1186/s40170-020-00217-6 |