SIX2 Regulates Human β Cell Differentiation from Stem Cells and Functional Maturation In Vitro

Generation of insulin-secreting β cells in vitro is a promising approach for diabetes cell therapy. Human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) are differentiated to β cells (SC-β cells) and mature to undergo glucose-stimulated insulin secretion, but molecula...

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Detalles Bibliográficos
Autores principales: Velazco-Cruz, Leonardo, Goedegebuure, Madeleine M., Maxwell, Kristina G., Augsornworawat, Punn, Hogrebe, Nathaniel J., Millman, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304247/
https://www.ncbi.nlm.nih.gov/pubmed/32460030
http://dx.doi.org/10.1016/j.celrep.2020.107687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304247/
https://www.ncbi.nlm.nih.gov/pubmed/32460030
http://dx.doi.org/10.1016/j.celrep.2020.107687

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