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Macrophages and Associated Ligands in the Aged Injured Nerve: A Defective Dynamic That Contributes to Reduced Axonal Regrowth

The regenerative capacity of injured peripheral nerves is diminished with aging. To identify factors that contribute to this impairment, we compared the immune cell response in young vs. aged animals following nerve injury. First, we confirmed that macrophage accumulation is delayed in aged injured...

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Detalles Bibliográficos
Autores principales: Stratton, Jo Anne, Eaton, Shane, Rosin, Nicole L., Jawad, Sana, Holmes, Alexandra, Yoon, Grace, Midha, Rajiv, Biernaskie, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304384/
https://www.ncbi.nlm.nih.gov/pubmed/32595489
http://dx.doi.org/10.3389/fnagi.2020.00174