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Combination of ferric ammonium citrate with cytokines involved in apoptosis and insulin secretion of human pancreatic beta cells related to diabetes in thalassemia

BACKGROUND: Diabetes mellitus (DM) is a common complication found in β-thalassemia patients. The mechanism of DM in β-thalassemia patients is still unclear, but it could be from an iron overload and increase of some cytokines, such as interleukin1-β (IL-1β) and tumor necrosis factor-α (TNF-α). The o...

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Detalles Bibliográficos
Autores principales: Rattanaporn, Patchara, Tongsima, Sissades, Mandrup-Poulsen, Thomas, Svasti, Saovaros, Tanyong, Dalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304432/
https://www.ncbi.nlm.nih.gov/pubmed/32587797
http://dx.doi.org/10.7717/peerj.9298