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Large Nanodiscs: A Potential Game Changer in Structural Biology of Membrane Protein Complexes and Virus Entry

Phospho-lipid bilayer nanodiscs have gathered much scientific interest as a stable and tunable membrane mimetic for the study of membrane proteins. Until recently the size of the nanodiscs that could be produced was limited to ~ 16 nm. Recent advances in nanodisc engineering such as covalently circu...

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Detalles Bibliográficos
Autores principales: Padmanabha Das, Krishna M., Shih, William M., Wagner, Gerhard, Nasr, Mahmoud L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304444/
https://www.ncbi.nlm.nih.gov/pubmed/32596222
http://dx.doi.org/10.3389/fbioe.2020.00539