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Loss of the Krüppel-like factor 4 tumor suppressor is associated with epithelial-mesenchymal transition in colorectal cancer

AIM: Colorectal cancer (CRC) is the third leading cancer-related cause of death due to its propensity to metastasize. Epithelial-mesenchymal transition (EMT) is a multistep process important for invasion and metastasis of CRC. Krüppel-like factor 4 (KLF4) is a zinc finger transcription factor highly...

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Detalles Bibliográficos
Autores principales: Agbo, Kimberley C., Huang, Jessie Z., Ghaleb, Amr M., Williams, Jennie L., Shroyer, Kenneth R., Bialkowska, Agnieszka B., Yang, Vincent W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304562/
https://www.ncbi.nlm.nih.gov/pubmed/32566755
http://dx.doi.org/10.20517/2394-4722.2019.35