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Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae

Curli play critical roles in biofilm formation, host cell adhesion, and colonization of inert surfaces in many Enterobacteriaceae. In Escherichia coli, curli biogenesis requires 7 curli-specific gene (csg) products—CsgA through G—working in concert. Of them, CsgG and CsgF are 2 outer membrane (OM)-l...

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Detalles Bibliográficos
Autores principales: Zhang, Manfeng, Shi, Huigang, Zhang, Xuemei, Zhang, Xinzheng, Huang, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304575/
https://www.ncbi.nlm.nih.gov/pubmed/32559189
http://dx.doi.org/10.1371/journal.pbio.3000748