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Control of the neuroprotective Lipocalin Apolipoprotein D expression by alternative promoter regions and differentially expressed mRNA 5’ UTR variants

The Lipocalin Apolipoprotein D (ApoD) is one of the few genes consistently overexpressed in the aging brain, and in most neurodegenerative and psychiatric diseases. Its functions include metabolism regulation, myelin management, neuroprotection, and longevity regulation. Knowledge of endogenous regu...

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Detalles Bibliográficos
Autores principales: Diez-Hermano, Sergio, Mejias, Andres, Sanchez, Diego, Gutierrez, Gabriel, Ganfornina, Maria D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304576/
https://www.ncbi.nlm.nih.gov/pubmed/32559215
http://dx.doi.org/10.1371/journal.pone.0234857