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Calcium-induced calcium release and type 3 ryanodine receptors modulate the slow afterhyperpolarising current, sI(AHP), and its potentiation in hippocampal pyramidal neurons

The slow afterhyperpolarising current, sI(AHP), is a Ca(2+)-dependent current that plays an important role in the late phase of spike frequency adaptation. sI(AHP) is activated by voltage-gated Ca(2+) channels, while the contribution of calcium from ryanodine-sensitive intracellular stores, released...

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Detalles Bibliográficos
Autores principales: Tedoldi, Angelo, Ludwig, Petra, Fulgenzi, Gianluca, Takeshima, Hiroshi, Pedarzani, Paola, Stocker, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304577/
https://www.ncbi.nlm.nih.gov/pubmed/32559219
http://dx.doi.org/10.1371/journal.pone.0230465