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Calcium-induced calcium release and type 3 ryanodine receptors modulate the slow afterhyperpolarising current, sI(AHP), and its potentiation in hippocampal pyramidal neurons
The slow afterhyperpolarising current, sI(AHP), is a Ca(2+)-dependent current that plays an important role in the late phase of spike frequency adaptation. sI(AHP) is activated by voltage-gated Ca(2+) channels, while the contribution of calcium from ryanodine-sensitive intracellular stores, released...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304577/ https://www.ncbi.nlm.nih.gov/pubmed/32559219 http://dx.doi.org/10.1371/journal.pone.0230465 |