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A recombinant gp145 Env glycoprotein from HIV-1 expressed in two different cell lines: Effects on glycosylation and antigenicity

The envelope glycoprotein (Env) of the human immunodeficiency virus (HIV), has been the primary target for the development of a protective vaccine against infection. The extensive N-linked glycosylation on Env is an important consideration as it may affect efficacy, stability, and expression yields....

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Detalles Bibliográficos
Autores principales: González-Feliciano, José A., Akamine, Pearl, Capó-Vélez, Coral M., Delgado-Vélez, Manuel, Dussupt, Vincent, Krebs, Shelly J., Wojna, Valerie, Polonis, Victoria R., Baerga-Ortiz, Abel, Lasalde-Dominicci, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304579/
https://www.ncbi.nlm.nih.gov/pubmed/32559193
http://dx.doi.org/10.1371/journal.pone.0231679