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Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice

Aging in mammals is the gradual decline of an organism’s physical, mental, and physiological capacity. Aging leads to increased risk for disease and eventually to death. Here, we show that Brd2 haploinsufficiency (Brd2+/-) extends lifespan and increases healthspan in C57B6/J mice. In Brd2+/- mice, l...

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Detalles Bibliográficos
Autores principales: Pathak, Shilpa, Stewart, William C. L., Burd, Christin E., Hester, Mark E., Greenberg, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304595/
https://www.ncbi.nlm.nih.gov/pubmed/32559200
http://dx.doi.org/10.1371/journal.pone.0234910