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Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer

Hepatocellular carcinoma (HCC), the most malignant form of primary liver cancer, is the fourth most prevalent cause of cancer mortality globally. It was recently discovered that the dietary fermentable fiber, inulin, can reprogram the murine liver to favor HCC development in a gut microbiota-depende...

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Detalles Bibliográficos
Autores principales: Chandrashekar, Darshan Shimoga, Golonka, Rachel M., Yeoh, Beng San, Gonzalez, David J., Heikenwälder, Mathias, Gerwirtz, Andrew T., Varambally, Sooryanarayana, Vijay-Kumar, Matam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304627/
https://www.ncbi.nlm.nih.gov/pubmed/32559205
http://dx.doi.org/10.1371/journal.pone.0234726