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Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer
Hepatocellular carcinoma (HCC), the most malignant form of primary liver cancer, is the fourth most prevalent cause of cancer mortality globally. It was recently discovered that the dietary fermentable fiber, inulin, can reprogram the murine liver to favor HCC development in a gut microbiota-depende...
Autores principales: | Chandrashekar, Darshan Shimoga, Golonka, Rachel M., Yeoh, Beng San, Gonzalez, David J., Heikenwälder, Mathias, Gerwirtz, Andrew T., Varambally, Sooryanarayana, Vijay-Kumar, Matam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304627/ https://www.ncbi.nlm.nih.gov/pubmed/32559205 http://dx.doi.org/10.1371/journal.pone.0234726 |
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