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Recurrent Amplification of the Osmotic Stress Transcription Factor NFAT5 in Adrenocortical Carcinoma

Tumorigenesis requires mitigation of osmotic stress and the transcription factor nuclear factor of activated T cells 5 (NFAT5) coordinates this response by inducing transcellular transport of ions and osmolytes. NFAT5 modulates in vitro behavior in several cancer types, but a potential role of NFAT5...

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Detalles Bibliográficos
Autores principales: Brown, Taylor C, Nicolson, Norman G, Man, Jianliang, Gibson, Courtney E, Stenman, Adam, Juhlin, C Christofer, Korah, Reju, Carling, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304660/
https://www.ncbi.nlm.nih.gov/pubmed/32587934
http://dx.doi.org/10.1210/jendso/bvaa060