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Recurrent Amplification of the Osmotic Stress Transcription Factor NFAT5 in Adrenocortical Carcinoma
Tumorigenesis requires mitigation of osmotic stress and the transcription factor nuclear factor of activated T cells 5 (NFAT5) coordinates this response by inducing transcellular transport of ions and osmolytes. NFAT5 modulates in vitro behavior in several cancer types, but a potential role of NFAT5...
Autores principales: | Brown, Taylor C, Nicolson, Norman G, Man, Jianliang, Gibson, Courtney E, Stenman, Adam, Juhlin, C Christofer, Korah, Reju, Carling, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304660/ https://www.ncbi.nlm.nih.gov/pubmed/32587934 http://dx.doi.org/10.1210/jendso/bvaa060 |
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