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LESA Cyclic Ion Mobility Mass Spectrometry of Intact Proteins from Thin Tissue Sections

[Image: see text] Liquid extraction surface analysis (LESA) is an ambient surface sampling technique that allows the analysis of intact proteins directly from tissue samples via mass spectrometry. Integration of ion mobility separation to LESA mass spectrometry workflows has shown significant improv...

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Detalles Bibliográficos
Autores principales: Sisley, Emma K., Ujma, Jakub, Palmer, Martin, Giles, Kevin, Fernandez-Lima, Francisco A., Cooper, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304663/
https://www.ncbi.nlm.nih.gov/pubmed/32271006
http://dx.doi.org/10.1021/acs.analchem.9b05169