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Control over Imidazoquinoline Immune Stimulation by pH-Degradable Poly(norbornene) Nanogels

[Image: see text] The reactivation of the innate immune system by toll-like receptor (TLR) agonists holds promise for anticancer immunotherapy. Severe side effects caused by unspecific and systemic activation of the immune system upon intravenous injection prevent the use of small-molecule TLR agoni...

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Detalles Bibliográficos
Autores principales: Kockelmann, Johannes, Stickdorn, Judith, Kasmi, Sabah, De Vrieze, Jana, Pieszka, Michaela, Ng, David Yuen W., David, Sunil A., De Geest, Bruno G., Nuhn, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304817/
https://www.ncbi.nlm.nih.gov/pubmed/32255626
http://dx.doi.org/10.1021/acs.biomac.0c00205