Combination vaccine based on citrullinated vimentin and enolase peptides induces potent CD4-mediated anti-tumor responses

BACKGROUND: Stress-induced post-translational modifications occur during autophagy and can result in generation of new epitopes and immune recognition. One such modification is the conversion of arginine to citrulline by peptidylarginine deiminase enzymes. METHODS: We used Human leukocyte antigen (H...

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Detalles Bibliográficos
Autores principales: Brentville, Victoria A, Metheringham, Rachael L, Daniels, Ian, Atabani, Suha, Symonds, Peter, Cook, Katherine W, Vankemmelbeke, Mireille, Choudhury, Ruhul, Vaghela, Poonam, Gijon, Mohamed, Meiners, Ghislaine, Krebber, Willem-Jan, Melief, Cornelis J M, Durrant, Lindy G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304843/
https://www.ncbi.nlm.nih.gov/pubmed/32561639
http://dx.doi.org/10.1136/jitc-2020-000560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304843/
https://www.ncbi.nlm.nih.gov/pubmed/32561639
http://dx.doi.org/10.1136/jitc-2020-000560

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