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Immunomodulation to enhance the efficacy of an HPV therapeutic vaccine

BACKGROUND: While prophylactic human papillomavirus (HPV) vaccines will certainly reduce the incidence of HPV-associated cancers, these malignancies remain a major health issue. PDS0101 is a liposomal-based HPV therapeutic vaccine consisting of the immune activating cationic lipid R-DOTAP and HLA-un...

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Detalles Bibliográficos
Autores principales: Smalley Rumfield, Claire, Pellom, Samuel T, Morillon II, Y Maurice, Schlom, Jeffrey, Jochems, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304848/
https://www.ncbi.nlm.nih.gov/pubmed/32554612
http://dx.doi.org/10.1136/jitc-2020-000612