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Immunomodulation to enhance the efficacy of an HPV therapeutic vaccine
BACKGROUND: While prophylactic human papillomavirus (HPV) vaccines will certainly reduce the incidence of HPV-associated cancers, these malignancies remain a major health issue. PDS0101 is a liposomal-based HPV therapeutic vaccine consisting of the immune activating cationic lipid R-DOTAP and HLA-un...
Autores principales: | Smalley Rumfield, Claire, Pellom, Samuel T, Morillon II, Y Maurice, Schlom, Jeffrey, Jochems, Caroline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304848/ https://www.ncbi.nlm.nih.gov/pubmed/32554612 http://dx.doi.org/10.1136/jitc-2020-000612 |
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