Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

[Image: see text] Molecular editing such as insertion, deletion, and single atom exchange in highly functionalized compounds is an aspirational goal for all chemists. Here, we disclose a photoredox protocol for the replacement of a single fluorine atom with hydrogen in electron-deficient trifluorome...

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Detalles Bibliográficos
Autores principales: Sap, Jeroen B. I., Straathof, Natan J. W., Knauber, Thomas, Meyer, Claudio F., Médebielle, Maurice, Buglioni, Laura, Genicot, Christophe, Trabanco, Andrés A., Noël, Timothy, am Ende, Christopher W., Gouverneur, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304874/
https://www.ncbi.nlm.nih.gov/pubmed/32379965
http://dx.doi.org/10.1021/jacs.0c03881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304874/
https://www.ncbi.nlm.nih.gov/pubmed/32379965
http://dx.doi.org/10.1021/jacs.0c03881

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