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Bidirectional Synthesis of the IJK Fragment of Ciguatoxin CTX3C by Sequential Double Ring-Closing Metathesis and Tsuji–Trost Allylation

[Image: see text] A novel four-step bidirectional strategy has been used to synthesize the IJK fragment of the marine polyether natural product CTX3C from a simple monocyclic precursor in a concise and efficient manner. The four-step bidirectional sequence involves ring-closing metathesis, alcohol o...

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Detalles Bibliográficos
Autores principales: Popadynec, Michael, Gibbard, Helen, Clark, J. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304930/
https://www.ncbi.nlm.nih.gov/pubmed/32306737
http://dx.doi.org/10.1021/acs.orglett.0c01238