Allosteric pluripotency as revealed by protein kinase A

The functional response of a signaling system to an allosteric stimulus often depends on subcellular conditions, a phenomenon known as pluripotent allostery. For example, a single allosteric modulator, Rp-cAMPS, of the prototypical protein kinase A (PKA) switches from antagonist to agonist depending...

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Detalles Bibliográficos
Autores principales: Byun, J. A., Akimoto, M., VanSchouwen, B., Lazarou, T. S., Taylor, S. S., Melacini, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304965/
https://www.ncbi.nlm.nih.gov/pubmed/32596469
http://dx.doi.org/10.1126/sciadv.abb1250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304965/
https://www.ncbi.nlm.nih.gov/pubmed/32596469
http://dx.doi.org/10.1126/sciadv.abb1250

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