Cargando…
Nuclear softening expedites interstitial cell migration in fibrous networks and dense connective tissues
Dense matrices impede interstitial cell migration and subsequent repair. We hypothesized that nuclear stiffness is a limiting factor in migration and posited that repair could be expedited by transiently decreasing nuclear stiffness. To test this, we interrogated the interstitial migratory capacity...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304973/ https://www.ncbi.nlm.nih.gov/pubmed/32596438 http://dx.doi.org/10.1126/sciadv.aax5083 |