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Long-distance modulation of bystander tumor cells by CD8(+) T cell-secreted IFNγ
T cell-secreted IFNγ can exert pleiotropic effects on tumor cells that include induction of immune checkpoints and antigen presentation machinery components, and inhibition of cell growth. Despite its role as key effector molecule, little is known about the spatiotemporal spreading of IFNγ secreted...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305033/ https://www.ncbi.nlm.nih.gov/pubmed/32566933 http://dx.doi.org/10.1038/s43018-020-0036-4 |