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Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum

Hyaluronan is widely used in cosmetics and pharmaceutics. Development of robust and safe cell factories and cultivation approaches to efficiently produce hyaluronan is of many interests. Here, we describe the metabolic engineering of Corynebacterium glutamicum and application of a fermentation strat...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Hu, Litao, Huang, Hao, Wang, Hao, Zhang, Tianmeng, Chen, Jian, Du, Guocheng, Kang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305114/
https://www.ncbi.nlm.nih.gov/pubmed/32561727
http://dx.doi.org/10.1038/s41467-020-16962-7