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MeCP2 regulates gene expression through recognition of H3K27me3

MeCP2 plays a multifaceted role in gene expression regulation and chromatin organization. Interaction between MeCP2 and methylated DNA in the regulation of gene expression is well established. However, the widespread distribution of MeCP2 suggests it has additional interactions with chromatin. Here...

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Detalles Bibliográficos
Autores principales: Lee, Wooje, Kim, Jeeho, Yun, Jung-Mi, Ohn, Takbum, Gong, Qizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305159/
https://www.ncbi.nlm.nih.gov/pubmed/32561780
http://dx.doi.org/10.1038/s41467-020-16907-0