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A dietary fatty acid counteracts neuronal mechanical sensitization

PIEZO2 is the essential transduction channel for touch discrimination, vibration, and proprioception. Mice and humans lacking Piezo2 experience severe mechanosensory and proprioceptive deficits and fail to develop tactile allodynia. Bradykinin, a proalgesic agent released during inflammation, potent...

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Detalles Bibliográficos
Autores principales: Romero, Luis O., Caires, Rebeca, Nickolls, Alec R., Chesler, Alexander T., Cordero-Morales, Julio F., Vásquez, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305179/
https://www.ncbi.nlm.nih.gov/pubmed/32561714
http://dx.doi.org/10.1038/s41467-020-16816-2