Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins

Whole-cell cross-linking coupled to mass spectrometry is one of the few tools that can probe protein–protein interactions in intact cells. A very attractive reagent for this purpose is formaldehyde, a small molecule which is known to rapidly penetrate into all cellular compartments and to preserve t...

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Detalles Bibliográficos
Autores principales: Tayri-Wilk, Tamar, Slavin, Moriya, Zamel, Joanna, Blass, Ayelet, Cohen, Shon, Motzik, Alex, Sun, Xue, Shalev, Deborah E., Ram, Oren, Kalisman, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305180/
https://www.ncbi.nlm.nih.gov/pubmed/32561732
http://dx.doi.org/10.1038/s41467-020-16935-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305180/
https://www.ncbi.nlm.nih.gov/pubmed/32561732
http://dx.doi.org/10.1038/s41467-020-16935-w

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