Cargando…

Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments

Intracellular trafficking of organelles, driven by kinesin-1 stepping along microtubules, underpins essential cellular processes. In absence of other proteins on the microtubule surface, kinesin-1 performs micron-long runs. Under crowding conditions, however, kinesin-1 motility is drastically impede...

Descripción completa

Detalles Bibliográficos
Autores principales: Henrichs, Verena, Grycova, Lenka, Barinka, Cyril, Nahacka, Zuzana, Neuzil, Jiri, Diez, Stefan, Rohlena, Jakub, Braun, Marcus, Lansky, Zdenek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305210/
https://www.ncbi.nlm.nih.gov/pubmed/32561740
http://dx.doi.org/10.1038/s41467-020-16972-5