Cargando…

Highly parallel lab evolution reveals that epistasis can curb the evolution of antibiotic resistance

Genetic perturbations that affect bacterial resistance to antibiotics have been characterized genome-wide, but how do such perturbations interact with subsequent evolutionary adaptation to the drug? Here, we show that strong epistasis between resistance mutations and systematically identified genes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lukačišinová, Marta, Fernando, Booshini, Bollenbach, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305214/ https://www.ncbi.nlm.nih.gov/pubmed/32561723 http://dx.doi.org/10.1038/s41467-020-16932-z

Ejemplares similares

Epistasis and the Evolution of Antimicrobial Resistance
por: Wong, Alex
Publicado: (2017)

Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis
por: Borrell, Sònia, et al.
Publicado: (2013)

Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA
por: Yokoyama, Maho, et al.
Publicado: (2018)

Pervasive Cryptic Epistasis in Molecular Evolution
por: Lunzer, Mark, et al.
Publicado: (2010)

Mutation and Epistasis in Influenza Virus Evolution
por: Lyons, Daniel M., et al.
Publicado: (2018)

Maternal-Zygotic Epistasis and the Evolution of Genetic Diseases
por: Priest, Nicholas K., et al.
Publicado: (2010)

Correction: Pervasive Cryptic Epistasis in Molecular Evolution
por: Lunzer, Mark, et al.
Publicado: (2010)

Epistasis and evolution: recent advances and an outlook for prediction
por: Johnson, Milo S., et al.
Publicado: (2023)

Mutators can drive the evolution of multi-resistance to antibiotics
por: Gifford, Danna R., et al.
Publicado: (2023)

Bacterial Subcellular Architecture, Structural Epistasis, and Antibiotic Resistance
por: Baquero, Fernando, et al.
Publicado: (2023)

Testing the Role of Genetic Background in Parallel Evolution Using the Comparative Experimental Evolution of Antibiotic Resistance
por: Vogwill, Tom, et al.
Publicado: (2014)

Phenotypic error threshold; additivity and epistasis in RNA evolution
por: Takeuchi, Nobuto, et al.
Publicado: (2005)

Evolution and polymorphism in the multilocus Levene model with no or weak epistasis
por: Bürger, Reinhard
Publicado: (2010)

Intramolecular Epistasis and the Evolution of a New Enzymatic Function
por: Noor, Sajid, et al.
Publicado: (2012)

Prevalence of Epistasis in the Evolution of Influenza A Surface Proteins
por: Kryazhimskiy, Sergey, et al.
Publicado: (2011)

Stability-mediated epistasis constrains the evolution of an influenza protein
por: Gong, Lizhi Ian, et al.
Publicado: (2013)

Modular epistasis and the compensatory evolution of gene deletion mutants
por: Rojas Echenique, José I., et al.
Publicado: (2019)

Epistasis between antibiotic tolerance, persistence, and resistance mutations
por: Levin-Reisman, Irit, et al.
Publicado: (2019)

Evolution of Amino Acid Propensities under Stability-Mediated Epistasis
por: Youssef, Noor, et al.
Publicado: (2022)

Epistasis Creates Invariant Sites and Modulates the Rate of Molecular Evolution
por: Patel, Ravi, et al.
Publicado: (2022)

An evolution-based high-fidelity method of epistasis measurement: Theory and application to influenza
por: Pedruzzi, Gabriele, et al.
Publicado: (2021)

Dominant resistance and negative epistasis can limit the co-selection of de novo resistance mutations and antibiotic resistance genes
por: Porse, Andreas, et al.
Publicado: (2020)

Patterns of Epistasis between Beneficial Mutations in an Antibiotic Resistance Gene
por: Schenk, Martijn F., et al.
Publicado: (2013)

An End to Endless Forms: Epistasis, Phenotype Distribution Bias, and Nonuniform Evolution
por: Borenstein, Elhanan, et al.
Publicado: (2008)

Epistasis between cultural traits causes paradigm shifts in cultural evolution
por: Pascual, Ignacio, et al.
Publicado: (2020)

Epistasis-Driven Evolution of the SARS-CoV-2 Secondary Structure
por: Alemrajabi, Mahsa, et al.
Publicado: (2022)

Bacterial motility can govern the dynamics of antibiotic resistance evolution
por: Piskovsky, Vit, et al.
Publicado: (2023)

Distribution of fitness effects of cross-species transformation reveals potential for fast adaptive evolution
por: Rathmann, Isabel, et al.
Publicado: (2022)

A Two-Locus System with Strong Epistasis Underlies Rapid Parasite-Mediated Evolution of Host Resistance
por: Ameline, Camille, et al.
Publicado: (2020)

Correction to: Distribution of fitness effects of cross-species transformation reveals potential for fast adaptive evolution
por: Rathmann, Isabel, et al.
Publicado: (2023)

The blackgrass genome reveals patterns of non‐parallel evolution of polygenic herbicide resistance
por: Cai, Lichun, et al.
Publicado: (2023)

Evolution Meets Disease: Penetrance and Functional Epistasis of Mitochondrial tRNA Mutations
por: Moreno-Loshuertos, Raquel, et al.
Publicado: (2011)

Identification of the potentiating mutations and synergistic epistasis that enabled the evolution of inter-species cooperation
por: Douglas, Sarah M., et al.
Publicado: (2017)

Immune Heterogeneity and Epistasis Explain Punctuated Evolution of SARS-CoV-2
por: Nielsen, Bjarke Frost, et al.
Publicado: (2022)

Host heterogeneity and epistasis explain punctuated evolution of SARS-CoV-2
por: Nielsen, Bjarke Frost, et al.
Publicado: (2023)

Widespread epistasis shapes RNA Polymerase II active site function and evolution
por: Duan, Bingbing, et al.
Publicado: (2023)

Proteostasis Environment Shapes Higher-Order Epistasis Operating on Antibiotic Resistance
por: Guerrero, Rafael F., et al.
Publicado: (2019)

The Evolution of Jefferson Lab's Control System
por: Bickley, M H, et al.
Publicado: (1999)

Predicting the evolution of antibiotic resistance
por: Schenk, Martijn F, et al.
Publicado: (2013)

Inhibiting the Evolution of Antibiotic Resistance
por: Ragheb, Mark N., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_d4tf7c4vftvhat5b92g8da41ue