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The role of MDM2–p53 axis dysfunction in the hepatocellular carcinoma transformation

Liver cancer is the second most frequent cause of cancer-related death globally. The main histological subtype is hepatocellular carcinoma (HCC), which is derived from hepatocytes. According to the epidemiologic studies, the most important risk factors of HCC are chronic viral infections (HBV, HCV,...

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Detalles Bibliográficos
Autores principales: Cao, Hui, Chen, Xiaosong, Wang, Zhijun, Wang, Lei, Xia, Qiang, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305227/
https://www.ncbi.nlm.nih.gov/pubmed/32595984
http://dx.doi.org/10.1038/s41420-020-0287-y