The secondary bile acids, ursodeoxycholic acid and lithocholic acid, protect against intestinal inflammation by inhibition of epithelial apoptosis

Increased epithelial permeability is a key feature of IBD pathogenesis and it has been proposed that agents which promote barrier function may be of therapeutic benefit. We have previously reported the secondary bile acid, ursodeoxycholic acid (UDCA), to be protective in a mouse model of colonic inf...

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Detalles Bibliográficos
Autores principales: Lajczak‐McGinley, Natalia K., Porru, Emanule, Fallon, Ciara M., Smyth, Jessica, Curley, Caitriona, McCarron, Paul A., Tambuwala, Murtaza M., Roda, Aldo, Keely, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305237/
https://www.ncbi.nlm.nih.gov/pubmed/32562381
http://dx.doi.org/10.14814/phy2.14456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305237/
https://www.ncbi.nlm.nih.gov/pubmed/32562381
http://dx.doi.org/10.14814/phy2.14456

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