Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formation

Nonsense-mediated mRNA decay (NMD) typifies an mRNA surveillance pathway. Because NMD necessitates a translation event to recognize a premature termination codon on mRNAs, truncated misfolded polypeptides (NMD-polypeptides) could potentially be generated from NMD substrates as byproducts. Here, we s...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Yeonkyoung, Park, Joori, Hwang, Hyun Jung, Kim, Byungju, Jeong, Kwon, Chang, Jeeyoon, Lee, Jong-Bong, Kim, Yoon Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305299/
https://www.ncbi.nlm.nih.gov/pubmed/32561765
http://dx.doi.org/10.1038/s41467-020-16939-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305299/
https://www.ncbi.nlm.nih.gov/pubmed/32561765
http://dx.doi.org/10.1038/s41467-020-16939-6

Ejemplares similares