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Substrate specificity of the TRAMP nuclear surveillance complexes

During nuclear surveillance in yeast, the RNA exosome functions together with the TRAMP complexes. These include the DEAH-box RNA helicase Mtr4 together with an RNA-binding protein (Air1 or Air2) and a poly(A) polymerase (Trf4 or Trf5). To better determine how RNA substrates are targeted, we analyze...

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Detalles Bibliográficos
Autores principales: Delan-Forino, Clémentine, Spanos, Christos, Rappsilber, Juri, Tollervey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305330/
https://www.ncbi.nlm.nih.gov/pubmed/32561742
http://dx.doi.org/10.1038/s41467-020-16965-4